Sir Henry Hallett Dale was an #English #biologist and #physiologist who isolated (1914) the #neur…

Sir Henry Hallett Dale was an #English #biologist and #physiologist who isolated (1914) the #neurotransmitter #acetylcholine from #ergot fungi.

In 1936 he shared the #NobelPrize for #Physiology or Medicine (with the German pharmacologist Otto Loewi) for discoveries in the chemical #transmission of #nerve #impulses.

Otto Loewi had shown that a substance released by electrical stimulation of the #VagusNerve was responsible for effecting changes in #heartbeat.

Following up this work, Dale showed that the substance is in fact acetylcholine, thus establishing that chemical as well as electrical stimuli are involved in nerve action.

He also worked on the properties of #histamine and related substances, including their actions in #allergic and #anaphylactic conditions.

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