Born 18 Apr 1905; died 27 Feb 1998 at age 92.
#American #pharmacologist was a medical research pioneer who was awarded a share of the #NobelPrize for Physiology or Medicine in 1988 (with Gertrude B. Elion and Sir James W. Black) for development of #drugs for several major #diseases.
In the 1950s, he and colleague Elion developed #Thioguanine and 6-mercaptopurine, that treated #Leukemia, and in 1957, #Azathioprine, used in treating severe #RheumatoidArthritis and other #autoimmune disorders. Their drug #Allopurinol was effective treatment for #Gout.
Other important drugs they developed include #pyrimethamine, an #antimalarial agent; #trimethoprim, a treatment for urinary and respiratory tract #infections; and #acyclovir, the first effective treatment for viral #Herpes.
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