Born 8 Jun 1947.
#American developmental #biologist who shared the 1995 #Nobel! Prize for Physiology or #Medicine, with #geneticists Edward B. Lewis and Christiane Nüsslein-Volhard, for discovering the #genetic controls of early #embryonic development.
Wieschaus worked together with Nüsslein-Volhard examining #mutations in 40,000 #fruitfly families.
They discovered (1980) that about 5,000 of the fly's 20,000 #genes are important to embryonic development and about 140 are essential. They formed the widely accepted #model that three sets of genes control #subdivision in the developing embryo: #gapgenes, #pair-rule genes and #segment-polarity genes. Their work helped scientists to better understand #congenital mutations in other animals, including #humans.
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