Gregg Leonard Semenza is an #American #biochemist, #geneticist and #oncologist who shared the 201…

Gregg Leonard Semenza is an #American #biochemist, #geneticist and #oncologist who shared the 2019 #NobelPrize in Physiology or #Medicine with William G. Kaelin Jr. and Peter J. Ratcliffe, for their work on how cells sense and adapt to oxygen availability.

Semenza made the ground-breaking discovery of the HIF-1 (#hypoxia-inducible factor 1), a #protein, which controls #genes in response to changes in #oxygen availability, and adjust how much oxygen is received by #cells.

This line of investigation has far-reaching implications in the treatment of various diseases, including #cancer, #heartattacks, anemia and #strokes.

For example, further study can be made to examine if cancer cells are seeking oxygen when they spread into surrounding tissues and the bloodstream which carries them around the body.

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