Born 6 Apr 1920.
American #biochemist who shared (with Edwin G. Krebs) the 1992 #NobelPrize for #Physiology or Medicine for the #discovery of “reversible #protein #phosphorylation as a biological regulatory mechanism” which governs the activities of proteins in #cells. They purified and characterized the first #enzyme of this type. Their discovery was a key to unlocking how #glycogen in the body breaks down into #glucose. It fostered techniques that prevent the body from rejecting #transplanted #organs. Their breakthrough also opened new doors for research into #cancer, #bloodpressure, #inflammatory reactions and #brain signals.
