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Born 1 Jul 1907; died 29 Mar 1997 at age 89.

#British #biochemist and virologist who collaborated with Frederick Bawden to demonstrate that the #genetic material found in #viruses is #RNA. Together they obtained about a dozen viruses, or strains of viruses, in semi-crystalline or even crystalline form, including tobacco mosaic virus (#TMV). Pirie demonstrated that the preparations contained small amounts of phosphorus and showed conclusively that all contained ribonucleic acid (RNA). This contradicted the early views of Wendell Stanley (a later Nobel laureate), who believed viruses consisted entirely of #protein. Bawden and Pirie realized that RNA might be the #infective #component of viruses; but they were unable to confirm this experimentally, and it was left until 1956 for others to establish. www.masterdoctorclinic.com

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#American #biochemist whose contributions in elucidating the chemical #structure of #antibodies w…

#American #biochemist whose contributions in elucidating the chemical #structure of #antibodies won him (with Rodney Porter) the #NobelPrize for #Medicine or Physiology in 1972. Edelman studied the structure of #human #immunoglobulin. He first split this large molecule into smaller portions, by reducing and splitting the disulfide bonds. Edelman proposed that the molecule contained two kinds of #polypeptide chains: light and heavy. From such studies, Porter proposed a structure for the antibody #ImmunoglobulinG (IgG) in 1962. Edelman aimed to work out the complete #amino-acid #sequence of IgG. As it contained 1330 amino acids it was by far the largest protein then attempted. By 1969 he announced the complete sequence. www.masterdoctorclinic.com

#American #biochemist whose contributions in elucidating the chemical #structure of #antibodies w… post imageRead full post

Alfred Goodman Gilman is an #American #pharmacologist who shared the 1994 #NobelPrize for Physiol…

Alfred Goodman Gilman is an #American #pharmacologist who shared the 1994 #NobelPrize for Physiology or #Medicine with American biochemist Martin Rodbell for their separate research in discovering molecules called #Gproteins, which are intermediaries in the multistep pathway #cells use to react to an incoming #signal, such as a #hormone or #neurotransmitter. Gilman and his co-workers used #genetic and #biochemical techniques to identify and purify the G protein. For all your health related queries and information and to Book your #Appointment and #Telemedicine or #onlineconsultation with our Best #Diabetologist & #PreventiveCardiologist #DrBJagadish Kindly Call or WhatsApp us on our dedicated patient care number @ 8093008191. Or Click on the link bellow 👇 https://wa.me/918093008191

Alfred Goodman Gilman is an #American #pharmacologist who shared the 1994 #NobelPrize for Physiol… post imageRead full post

Gregg Leonard Semenza is an #American #biochemist, #geneticist and #oncologist who shared the 201…

Gregg Leonard Semenza is an #American #biochemist, #geneticist and #oncologist who shared the 2019 #NobelPrize in Physiology or #Medicine with William G. Kaelin Jr. and Peter J. Ratcliffe, for their work on how cells sense and adapt to oxygen availability. Semenza made the ground-breaking discovery of the HIF-1 (#hypoxia-inducible factor 1), a #protein, which controls #genes in response to changes in #oxygen availability, and adjust how much oxygen is received by #cells. This line of investigation has far-reaching implications in the treatment of various diseases, including #cancer, #heartattacks, anemia and #strokes. For example, further study can be made to examine if cancer cells are seeking oxygen when they spread into surrounding tissues and the bloodstream which carries them around the body. www.masterdoctorclinic.com

Gregg Leonard Semenza is an #American #biochemist, #geneticist and #oncologist who shared the 201… post imageRead full post

Born 30 Jun 1926.

#American #biochemist who made “fundamental studies of the biochemistry of #NucleicAcids , with particular regard to #recombinant-DNA” techniques for which he shared the #NobelPrize for #Chemistry in 1980 (with Walter Gilbert and Frederick Sanger). #Berg's pioneering #experiment, in which he was the first person to construct a recombinant-DNA molecule, initiated #GeneticEngineering . Such molecules contain parts of #DNA from different #species, for example, a #chromosome from a #virus combined with #genes from a #bacterial chromosome. DNA molecules from viruses, being relatively small, are useful for such investigations. Important practical applications now include the manufacture of human #hormone with the aid of bacteria. www.masterdoctorclinic.com

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Born 29 Jun 1893; died 28 Jun 1972 at age 78.

Prasanta Chandra Mahalanobis was an #Indian #statistician who set up large-scale #surveys, applied statistical theory and created institutions to carry out such work. He studied #physics and #mathematics at the University of #Cambridge, and became  interested in statistics. He returned to India in 1915. Although he began a teaching career in physics, he turned to statistics in applications of #anthropology, #meteorology and #biology. He established the #IndianStatisticalInstitute in #Calcutta (17 Dec 1931). The #MahalanobisDistance was his #innovation in statistics to compare two #data sets. He also devised #fractile #graphical #analysis to study #socioeconomic conditions. He applied statistics to issues of #crop yields and planning for #flood control. www.masterdoctorclinic.com

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" Father of Mitochondrial Medicine "

Born 29 Jun 1914; died 22 May 2007 at age 92. #Swedish #endocrinologist who coined the term #MitochondrialMedicine. He was a productive #researcher in that field (1950s-1990s). Notably, he identified (1988) the cause of a number of certain diseases, including #diabetes, was imbalances of the #oxidation process. #LuftDisease was the first #biochemically defined #mitochondrial #disease. He was the first to demonstrate the diabetes control was aggravated by #stress hormones  and #inheritance played a role in the #cells' production of #insulin. He was an important leader in advancing the care of diabetes patients including providing #nurses in diabetes wards with specialized training. www.masterdoctorclinic.com

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Born 29 Jun 1861; died 28 Jul 1939 at age 78.

#American #surgeon who came from a family of surgeons. He practiced with his father, Dr. William Worrell Mayo, and brother, Dr. Charles Mayo. They specialized in #surgery, #pioneering the concept of #grouppractice, and were renowned for adopting new techniques. Based in Rochester, Minn., their practice subsequently developed into the #MayoClinic, which opened its own building in 1914. For more Details and To Book your Appointment or for a #Telemedicine or #onlineconsultation with renowned #Diabetologist and #PreventiveCardiologist #DrBJagadish Kindly Call or WhatsApp us on our dedicated patient care number @ 8093008191. Or Click on the link bellow 👇 https://wa.me/918093008191 To get more Updates and Information regarding Health, Diseases and Wellness... Login to our Website www.masterdoctorclinic.com # Like our Facebook Page https://www.facebook.com/masterdoctorclinic/ https://www.facebook.com/masterdoctorwellness/ # Join our Facebook Group https://www.facebook.com/groups/masterdoctorwellness/?ref=share # Like Subscribe & Share our YouTube Channel https://www.youtube.com/channel/UCjmMxvbA91prRzN58oJUX9Q # Follow us on Instagram www.instagram.com/masterdoctorwellness #drbjagadish #masterdoctor #DiabetesClinic #Telemedicine #onlineconsultation #Diabetologist #Odisha #health #awareness

Born 29 Jun 1861; died 28 Jul 1939 at age 78. post imageRead full post

#American #physicist and #radiologist who invented the #ACTA (Automatic Computerized Transverse A…

#American #physicist and #radiologist who invented the #ACTA (Automatic Computerized Transverse Axial) diagnostic #X-ray scanner, the first whole-body computerized tomography (#CT) machine (U.S. patent no. 3,922,552) which revolutionized medical #diagnosis. The ACTA can make a #three-dimensional analysis of all organs and parts of the body in a series of #cross-section images using thin X-ray beams and high power computer processing of the collected data. Using the ACTA, diagnosis of #tumours, #infection or #bleeding is possible even deep within large #organs, and it can give improved #radiationtherapy for #cancer. The framework could be tilted to give results from planes other than vertical. www.masterdoctorclinic.com

#American #physicist and #radiologist who invented the #ACTA (Automatic Computerized Transverse A… post imageRead full post

" Father of Modern Orthopedic Surgery "

Born 28 Jun 1857; died 14 Jan 1933 at age 75. #English #orthopaedic #surgeon who has been called the founder of modern orthopaedic surgery. He was a nephew of Hugh Owen Thomas and became one of his apprentices in Liverpool. On 22 Feb 1896, #Jones published the first report of the clinical use of an #X-ray to locate a bullet in a wrist, for which equipment was provided by Oliver Lodge. Jones co-founded medical associations, including the #BritishOrthopaedicSociety and orthopaedic hospitals. During WWI, he led the orthopaedic section of the #British Forces. Jones advocated #tendon #transplantation, #bonegrafting, and other #conservative, #restorative #procedures. "Time stood still," it has been said, when Jones operated. He wrote several important books on orthopaedics. www.masterdoctorclinic.com

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" First Transplant Surgeon "

Born 28 Jun 1873; died 5 Nov 1944 at age 71. #French-American #surgeon and biologist who received the 1912 #NobelPrize for Physiology or #Medicine for developing a method of #suturing #bloodvessels. He moved to the #UnitedStates in 1905. As a member of the staff of the #RockefellerInstitute, he did notable work on the problem of keeping #tissue alive after removal from a living #organism. The most famous example was a piece of tissue from the heart of a chicken #embryo, which was kept alive from 1912 to 1946, at which time the experiment was deliberately ended. Techniques developed by Carrel have made possible the #surgical #transplantation of blood #vessels and body #organs.

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Born 28 Jun 1824; died 9 Jul 1880 at age 56.

#French #surgeon who was closely associated with the development of modern #physical #anthropology in France and whose study of #brain lesions contributed significantly to understanding the origins of #aphasia, the loss or #impairment of the ability to form or articulate #words. His #research was largely devoted to the comparative study of the #craniums of the various #human races. He established (1861) that the seats of articulate #speech were in the left #frontal region of the brain, now known as the convolution of #Broca. This was the first time an #anatomical link had been made between a location and in the brain and its function. He founded the anthropology laboratory at the École des Hautes. www.masterdoctorclinic.com

Born 28 Jun 1824; died 9 Jul 1880 at age 56. post imageRead full post