#American #pharmacologist who, along with Robert F. Furchgott and Ferid Murad, was co-awarded the…

#American #pharmacologist who, along with Robert F. Furchgott and Ferid Murad, was co-awarded the 1998 #NobelPrize in #Physiology or Medicine for the discovery that #OitricOxide (NO) acts as a #signaling molecule in the #cardiovascular system, an entirely new mechanism by which #bloodvessels in the body #relax and widen.

At first, major professional journals refused to publish his contention that a substance that is basic to #nitroglycerin and part of the #chemistry of smog is also crucial to the life process.

But over the years, others repeated his work and confirmed his discovery that nitric oxide is a #neurotransmitter that is, says Ignarro, "perhaps the most widespread signaling molecule that allows a variety of different #cell types to #communicate with one another."

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