René (Jules) Dubos was a French-born American microbiologist, environmentalist, and author who pi…
René (Jules) Dubos was a French-born American microbiologist, environmentalist, and author who pioneered research in isolating antibacterial substances from certain soil microorganisms and the discovery of major antibiotics.
In 1938, he discovered ribonuclease, a simple 3D enzyme, but an early contribution to research on the most basic functions of life.
In 1939, Dubos showed that a soil bacterium was capable of decomposing the starchlike capsule of the pneumococcus bacterium, rendering it harmless - unable to cause pneumonia.
From the soil microbe Bacillus brevis, he isolated tyrothricin, that was highly toxic to a wide range of bacteria.
Other research included acquired immunity, tuberculosis, and bacteria of the gastrointestinal tract. He died on his birthday.
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