Born 2 Jun 1850; died 29 Mar 1935 at age 84.

#English #physiologist and co-inventor of the #prone-pressure method (#Schafer method) of #artificial #respiration adopted by the #RoyalLifeSavingSociety.

In 1894, Sharpey-Schafer (with George Oliver) (1841-1915) demonstrated that the action of a specific hormone—#adrenaline (#epinephrine), an extract of the #adrenalgland—on #bloodvessels and #muscle contraction.

Upon injection into normal animals it produced a striking elevation in blood pressure. They also noted that the smooth muscles of the animal's bronchi relaxed. Their work stimulated interest in the study of the nature and functions of #hormones. Later, adrenaline became the first hormone to be isolated and crystallized.

Sharpey-Schafer also suspected that another hormone was produced by the islets of #Langerhans in the #pancreas. He adopted the name #insulin (1914, from the Latin for "island") independently coining the same word used by J. DeMeyer (1909 in a paper in French) for a secretion of the pancreas.

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